Plague Inc.is a simulation game that many of you might have heard of.

Choose A Good Starter Country

Choosing a starting country should not be taken lightly.

A poor choice of starting country can lead to an early defeat and make spreading your disease extremely difficult.

Palworld pals looking at the camera with viral crowns floating around them

However, it is not enough to just have airports and ports; they also need to be popular.

Some countries have airports and ports, but they are not very busy, which can be a disadvantage.

Challenging Countries As Starting Locations

Starting in a wealthy country can make things much more difficult.

The player is about to choose Saudi Arabia as their starting country in Plague Inc

Moreover,countries with few borders will make it harderto spread your disease.

Control Random Mutations By Devolving

Over time, some of your diseases may develop random mutations.

If you aim to infect as many countries as possible stealthily, dont forget to devolve.

The warning screen that appears when a symptom is devolved in Plague Inc

If you are playing above the normal difficulty level, you will be playing against the clock.

Therefore, playing stealthily might not be a good strategy.

You may need toplay a bit more offensively.

There are DNA bubbles appearing in Saudi Arabia and Egypt in Plague Inc

However, in some types of diseases, devolving may require you to spend points.

Since theVirus disease punch in mutates constantly, it can be very difficult to control.

Therefore, devolving is crucial to keep it under control.

Greenland remains uninfected state in Plague Inc.

Playing stealthily all the way through and constantly sticking to this strategy is not a good idea.

you’re gonna wanna know when to stop playing stealthily.

Playing aggressively iseffective for gaining more DNA quickly.

Plague selection screen in Plague Inc

Additionally, to maximize the yield from red bubbles, you should not keep your Severity stat too low.

If your Severity is low, you will get less DNA from red bubbles.

Therefore,playing aggressively can be more rewarding.

News event screen in Plague Inc

Orange DNA bubblesappear more frequently at the beginning of the gameand provide small DNA bonuses.

However, you cannot rely on them in the mid to late stages of the game.

Dont Delay Infecting Greenland

Greenland can be one of the most difficult countries to infect.

Russia’s attribute lists in Plague Inc

This is due to its low population, having only a port, and its cold climate.

To do this, develop traits targeting Rural, Cold, and Humid conditions.

Additionally, you might easily reach Greenlandfrom Norway as well.

Player unlocks Projectile Vomiting combo in Plague Inc

When your disease is detected, countries will close their ports and airports.

Therefore, you should infect everywhere and adapt your disease to every country before its too late.

Therefore, you should unlock Bacterial Resilience, Cold Resistance, and Heat Resistance as soon as possible.

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Virus

Due to its rapid mutation, it can quickly get out of your control.

Continuously devolving will become increasingly expensive.

You shouldprioritize Transmissions and abilities.

Indie Games

Fungus

Spreading this disease with classic transmissions is not easy.

You shouldfrequently use Spore abilities.

Parasite

This disease starts with high Severity.

Plague Inc

You should focus ondeveloping traits that increase your Infectivity.

Prion

This disease begins with difficulty for scientists to find a cure.

You should play to make this even more challenging.

Since it is also hard to spread, you shouldinvest extra in Transmissions.

Nano-Virus

Cure research for this disease will start immediately at the beginning of the game.

Therefore, you need tofrequently use Nano-Virus’s special abilitiesto disrupt cure research.

Bio-Weapon

This disease becomes more lethal over time, making it difficult to control.

You shoulduse special abilities to manage its lethality.Unlocking Annihilate can quickly guarantee victory.

If you develop the Nausea symptom, the infection will spread more effectively.

Similarly, you might see news announcing the ‘ICure equipment’.

In this case, you’re free to unlock the Sweating symptom to render this event ineffective.

Using events to your advantageand paying attention to the measures countries are taking will always benefit you.

Therefore, you shouldcheck the attributes of countries where your disease is weakor struggling to spread.

This way, you might develop your disease to target those specific countries.

Make Your Disease More Effective Using Combos

Another way tomake your disease more effectiveis by using combos.

Becoming familiar with combos as soon as possible will be to your advantage.

The World Health Organization play Plague Inc: The Cure.

This new expansion from developers Ndemic has players fight the pandemic.